Innovative model-based strategies to streamline drug-development and to optimize the “cost-to-decision”
PharmacoMetrica is a global provider of consulting services in Pharmacometrics. Our areas of expertise include population PK and PK-PD modelling, exposure-response modelling, rationale for dose selection, disease progression, model-based meta analysis of therapeutic area data, optimal study design for PK-PD, Bayesian modelling, Clinical Trial Simulation to support decision making and trial design evaluation, and physiologically-based modelling
Our Mission
To help Pharmaceutical and Biotechnology organizations to implement more innovative and efficient drug development processes.
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Apply population model-based approach and clinical trial simulations to enhance clinical development plans
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Use leading edge statistical techniques, including adaptive learning and confirming approaches, to implement resource-efficient trial design methodologies
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Use a pharmacometrics approach to characterize the inherent risks of a given clinical development plan or a protocol design and to support early discontinuation of less promising compounds
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Use model-based approach to enable the rational assessment of dose selection, clinical trial design, in-licensing drug opportunities and labeling requirements
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Use a model-based approach to differentiate a product from competitors increasing the value of the franchise program
Our Strategy
PharmacoMetrica services and solutions will reduce time, cost and risk of drug development activities.
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The gain in efficiency (cost to decision) associated with implementing innovative model-based drug development strategies can be measured by:
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the time saved in the conduct of a well designed study,
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the ratio between the amount of information gathered and the cost of the trial (including the optimization of the number of patients to enroll necessary to detect a signal),
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the early detection of signal of efficacy or lack of efficacy which can trigger the decision to speed up or terminate the product development (redirecting resources),
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the reduction of overall time needed for filing new drug applications
Our Organization
PharmacoMetrica is composed by talented and highly-trained scientists with exceptional expertise and experience in pharmacometrics and clinical pharmacology.
Our track record includes numerous publications in peer-reviewed journals and invited presentations on Model-Based Drug Development delivered at international symposia and meetings.
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The staff of PharmacoMetrica has the depth and breadth of skills and expertise in applying Model-Based Drug Development to overcome the challenges articulated in the Critical Path initiative.